Double diastereoselection explains limitations in synthesizing mannose-containing beta-(1,3)-glucans.

Abstract

It is known that 3-O-glycosylation of glucosidic acceptors bearing acyl groups in the 4 and 6 positions instead of a 4,6-O-benzylidene ring mainly affords alpha-glycosides. Described here is an unexpected stereochemical outcome for elongation at glucose O-3 of a beta-d-Glcp-(1-->3)-alpha-d-Manp disaccharide using peracetylated ethyl thioglucoside as a donor… (More)
DOI: 10.1016/j.carres.2010.04.018

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Cite this paper

@article{Sylla2010DoubleDE, title={Double diastereoselection explains limitations in synthesizing mannose-containing beta-(1,3)-glucans.}, author={Balla Sylla and Karine Descroix and Christophe Pain and C{\'e}dric Gervaise and Frank Jamois and J L Yvin and Laurent Legentil and Caroline Nugier-Chauvin and R Daniellou and Vincent Ferri{\`e}res}, journal={Carbohydrate research}, year={2010}, volume={345 10}, pages={1366-70} }