Double cortical stimulation in amyotrophic lateral sclerosis.

  title={Double cortical stimulation in amyotrophic lateral sclerosis.},
  author={Takanori Yokota and Aihide Yoshino and Akira Inaba and Yukinobu Saito},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={61 6},
OBJECTIVE Transcranial double magnetic stimulation on the motor cortex was used to investigate central motor tract function in 16 patients with amyotrophic lateral sclerosis, five with spinal muscular atrophy, and 16 age matched normal controls. METHODS Surface EMG responses were recorded from the relaxed abductor pollicis brevis (APB) muscle. RESULTS Responses to test stimuli were markedly attenuated by a subthreshold conditioning stimulus given at a condition-test (C-T) interval of 1-4 ms… CONTINUE READING
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