Double-blind trial of botulinum toxin for treatment of focal hand dystonia.

@article{Cole1995DoubleblindTO,
  title={Double-blind trial of botulinum toxin for treatment of focal hand dystonia.},
  author={Rebel A. Cole and Mark Hallett and Leonardo G. Cohen},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={1995},
  volume={10 4},
  pages={466-71}
}
Ten patients with focal dystonia of the hand, all of whom had benefited in an open-label study of botulinum toxin, were treated with botulinum toxin-A in a double-blind study. Response was assessed by three measures: (a) subjective rating, provided by patients' reports of the effect of the injections on the dystonia; (b) objective testing, consisting of manual muscle testing (MRC scale) to measure muscle strength in all patients, timing of a writing sample and counting the number of errors of… CONTINUE READING