Double-blind study on the effect of cigarette smoking on the chromosomes of human peripheral blood lymphocytes in vivo.

@article{Obe1982DoubleblindSO,
  title={Double-blind study on the effect of cigarette smoking on the chromosomes of human peripheral blood lymphocytes in vivo.},
  author={Guenter Obe and Hermann Josef Vogt and Stephan Madle and A Fahning and W. D. Heller},
  journal={Mutation research},
  year={1982},
  volume={92 1-2},
  pages={309-19}
}
A double-blind study with 170 smokers and 124 non-smokers revealed a doubling of the frequencies of exchange-type aberrations in the peripheral blood lymphocytes of smokers as compared with non-smokers. Smokers (N = 24) had 1 SCE more per metaphase than non-smokers (N = 20), an effect that is significant but low when compared with the effect on structural… CONTINUE READING