Double-blind controlled trial of lecithinized superoxide dismutase in patients with idiopathic interstitial pneumonia – short term evaluation of safety and tolerability

@inproceedings{Kamio2014DoubleblindCT,
  title={Double-blind controlled trial of lecithinized superoxide dismutase in patients with idiopathic interstitial pneumonia – short term evaluation of safety and tolerability},
  author={Koichiro Kamio and Arata Azuma and Ken Ohta and Yukihiko Sugiyama and Toshihiro Nukiwa and Shoji Kudoh and Tohru Mizushima},
  booktitle={BMC pulmonary medicine},
  year={2014}
}
BACKGROUND Idiopathic interstitial pneumonias such as idiopathic pulmonary fibrosis or fibrotic nonspecific interstitial pneumonia are irreversible progressive pulmonary diseases that often have fatal outcomes. Although the etiology of idiopathic interstitial pneumonias is not yet fully understood, anti-fibrotic and anti-inflammatory agents have shown limited therapeutic effectiveness. Reactive oxygen species and their cytotoxic effects on the lung epithelial cells have been reported to… CONTINUE READING
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