Double-blind controlled study of botulinum toxin in adductor spasmodic dysphonia.

  title={Double-blind controlled study of botulinum toxin in adductor spasmodic dysphonia.},
  author={D D Troung and Michael Rontal and M A Rolnick and andWilliamJ. Aronson and K L Mistura},
  journal={The Laryngoscope},
  volume={101 6 Pt 1},
The treatment of adductor spasmodic dysphonia using botulinum toxin A was conducted in 13 patients as a double-blind, placebo-controlled study. Patients were diagnosed independently by an interdisciplinary team consisting of speech pathologists, an otolaryngologist, and a neurologist. The toxin or saline was injected into each thyroarytenoid muscle under electromyographic and laryngoscopic guidance. Botulinum toxin A markedly reduced perturbation, decreased fundamental frequency range, and… CONTINUE READING

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