Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration.

@article{Horsfall1979DoubleBC,
  title={Double blind controlled comparison of aspirin, allopurinol and placebo in the management of arthralgia during pyrazinamide administration.},
  author={P A Horsfall and John Plummer and Walter Allan and David J Girling and Anthony J. Nunn and Wallace Fox},
  journal={Tubercle},
  year={1979},
  volume={60 1},
  pages={13-24}
}
Chinese patients with arthralgia during treatment with an antituberculosis regimen containing pyrazinamide were allocated at random to 3 anti-arthralgia treatment series in a controlled double-blind study. One series (18 patients) received soluble aspirin 2.4 g daily, the second (23 patients) allopurinol 200 mg daily, and the third (19 patients) placebo only, for 8 weeks. The response was assessed both by independent assessors and by the patients themselves using a diary card. The serum uric… CONTINUE READING

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