Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study.

@article{Sikich2008DoubleblindCO,
  title={Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) study.},
  author={Linmarie Sikich and Jean A. Frazier and Jon M. McClellan and Robert L. Findling and Benedetto Vitiello and Louise Ritz and Denisse Marion-Landais Ambler and Madeline Puglia and Ann E Maloney and Emily Michael and Sandra E. A. de Jong and Karen Slifka and Nancy Noyes and Stefanie A Hlastala and Leslie Pierson and Nora Mcnamara and Denise Delporto-Bedoya and Robert Anderson and Robert M. Hamer and Jeffrey A. Lieberman},
  journal={The American journal of psychiatry},
  year={2008},
  volume={165 11},
  pages={1420-31}
}
OBJECTIVE Atypical (second-generation) antipsychotics are considered standard treatment for children and adolescents with early-onset schizophrenia and schizoaffective disorder. However, the superiority of second-generation antipsychotics over first-generation antipsychotics has not been demonstrated. This study compared the efficacy and safety of two second-generation antipsychotics (olanzapine and risperidone) with a first-generation antipsychotic (molindone) in the treatment of early-onset… CONTINUE READING
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