Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting.

@article{Hengge2003DoubleblindRP,
  title={Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting.},
  author={Ulrich R. Hengge and Kristin Stocks and Heidi Wiehler and Sandy Faulkner and Stefan Esser and Christine H. Lorenz and Walter Jentzen and Dagmar Hengge and Manfred Goos and Robert E Dudley and Gary L. Ringham},
  journal={AIDS},
  year={2003},
  volume={17 5},
  pages={699-710}
}
BACKGROUND Despite highly active antiretroviral therapy (HAART), chronic involuntary weight loss still remains a serious problem in the care of HIV patients. Various alterations in energy metabolism and endocrine regulation have been found to cause loss of lean body mass (LBM) and body cell mass (BCM). Previous studies in HIV-positive men undergoing androgen replacement therapy or treatment with recombinant growth hormone (rGH) have shown partial restoration of LBM, but these treatments have… CONTINUE READING

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