Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule.

@article{Cols2006DoubleblindPS,
  title={Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule.},
  author={Carlos Col{\'a}s and Susana Monz{\'o}n and M{\'o}nica Venturini and Apolinar Lezaun},
  journal={The Journal of allergy and clinical immunology},
  year={2006},
  volume={117 4},
  pages={810-6}
}
BACKGROUND The inhalation of Salsola kali pollen is a common cause of respiratory diseases in Europe and North America. OBJECTIVE To evaluate the efficacy and safety of a depigmented and glutaraldehyde-polymerized therapeutic vaccine of S kali. METHODS The trial was randomized, double-blind, and placebo-controlled using a rush protocol in the build-up phase. Sixty patients with rhinoconjunctivitis (19 also had mild asthma) were randomly allocated to receive either active treatment… CONTINUE READING

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