Double-blind, placebo-controlled evaluation of grass pollen specific immunotherapy with oral drops administered sublingually or supralingually.

@article{Panzner2008DoubleblindPE,
  title={Double-blind, placebo-controlled evaluation of grass pollen specific immunotherapy with oral drops administered sublingually or supralingually.},
  author={Petr Panzner and Mark Petr{\'a}{\vs} and T. Sykora and Izabela K. Lesna},
  journal={Respiratory medicine},
  year={2008},
  volume={102 9},
  pages={1296-304}
}
Forty-one patients suffering from grass pollen allergy underwent specific immunotherapy with standardized allergen extract consisting of six grass pollens (H-Al per os) administered either sublingually or supralingually for one year. In order to investigate clinical and immunological changes induced by the administration of allergens via the oral mucosa, the double-blind, placebo-controlled, randomized design of the trial with 30 other patients enrolled in placebo groups was applied. Specific… CONTINUE READING

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