Double-blind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis.

@article{Calin1977DoubleblindMP,
  title={Double-blind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis.},
  author={Andrei Calin and Robert M Bennett and S Sukhupunyaraksa and Allan L. Goldman and H E Montoya and William M. O'Brien and Vincenzo Giuliano and Frank R. Schmid and Robert F. Willkens and H Y Sakofsky},
  journal={The Journal of rheumatology},
  year={1977},
  volume={4 2},
  pages={
          153-7
        }
}
A double-blind parallel multi-centre study of 102 patients with rheumatoid arthritis (RA) was performed, comparing ibuprofen (1200-2400 mg daily) and ketoprofen (150-300 mg daily) a new non-steroidal, anti-inflammatory agent, over a three month period. Ketoprofen was well tolerated and shown to have comparable efficacy with ibuprofen. Longterm efficacy and tolerance studies are indicated.