Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte.

@article{Wang2011DoubleAA,
  title={Double antioxidant activities of rosiglitazone against high glucose-induced oxidative stress in hepatocyte.},
  author={Xin Wang and Zhao Wang and Jiang Z Liu and Jun Xiang Hu and Hong Lei Chen and Wen Li Li and Chun Xu Hai},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2011},
  volume={25 4},
  pages={839-47}
}
Chronic hyperglycemia is the hallmark of diabetes and its complication. High glucose-induced excessive reactive oxygen species (ROS) production has been considered to play an important role in the development of diabetes. However, the influence of high glucose on the liver remains to be clarified. Rosiglitazone (RSG) is a member of thiazolidinediones (TDZs) family, which is the ligand of the of nuclear transcription factor peroxisome proliferator-activated receptor-γ (PPARγ), being used… CONTINUE READING

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