Double-Blind Study of 5-Hydroxytryptophan versus Placebo in the Treatment of Primary Fibromyalgia Syndrome

@article{Caruso1990DoubleBlindSO,
  title={Double-Blind Study of 5-Hydroxytryptophan versus Placebo in the Treatment of Primary Fibromyalgia Syndrome},
  author={Innocenzo Caruso and P. C. Sarzi Puttini and Marco Cazzola and Valeria Azzolini},
  journal={Journal of International Medical Research},
  year={1990},
  volume={18},
  pages={201 - 209}
}
A double-blind, placebo-controlled study of the efficacy and tolerability of 5-hydroxytryptophan (5-HTP) was conducted in 50 patients with primary fibromyalgia syndrome. All the clinical parameters studied were significantly improved by treatment with 5-HTP and only mild and transient side-effects were reported. Further controlled studies are required to define properly the value of 5-HTP in patients with primary fibromyalgia syndrome. 
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