Double-Blind, Placebo-Controlled Study of the Efficacy of Trazodone in Alcohol Post-Withdrawal Syndrome: Polysomnographic and Clinical Evaluations

@article{Bon2003DoubleBlindPS,
  title={Double-Blind, Placebo-Controlled Study of the Efficacy of Trazodone in Alcohol Post-Withdrawal Syndrome: Polysomnographic and Clinical Evaluations},
  author={O. Le Bon and J. Murphy and L. Staner and G. Hoffmann and N. Kormoss and M. Kentos and P. Dupont and K. Lion and I. Pelc and P. Verbanck},
  journal={Journal of Clinical Psychopharmacology},
  year={2003},
  volume={23},
  pages={377-383}
}
  • O. Le Bon, J. Murphy, +7 authors P. Verbanck
  • Published 2003
  • Psychology, Medicine
  • Journal of Clinical Psychopharmacology
  • Alcohol detoxification is accompanied by sustained difficulties in sleep initiation and maintenance. These difficulties are thought to be an important cause of relapse to alcohol use. However, the treatment of sleep problems with hypnotic drug is made difficult by cross-tolerance between benzodiazepines and alcohol. In this report, we evaluated the capacity of trazodone (TRZ), a second-generation antidepressant with anxiolytic and sedative properties, to increase the sleep efficiency in alcohol… CONTINUE READING
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