Dosing modifications of targeted cancer therapies in patients with special needs: evidence and controversies.

@article{Ng2012DosingMO,
  title={Dosing modifications of targeted cancer therapies in patients with special needs: evidence and controversies.},
  author={Terence Ng and Alexandre Chan},
  journal={Critical reviews in oncology/hematology},
  year={2012},
  volume={81 1},
  pages={58-74}
}
Targeted therapies have revolutionized the treatment of malignancies over the past decade. These agents are generally regarded to posses fewer systemic side effects than traditional cytotoxic chemotherapies. However, patients manifesting organ dysfunction or drug interactions with concurrent medications may require dosing modifications of their targeted… CONTINUE READING