Dosimetry of 60/61/62/64Cu-ATSM: a hypoxia imaging agent for PET

@article{Laforest2004DosimetryO6,
  title={Dosimetry of 60/61/62/64Cu-ATSM: a hypoxia imaging agent for PET},
  author={Richard Laforest and Farrokh Dehdashti and Jason S Lewis and Sally W. Schwarz},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2004},
  volume={32},
  pages={764-770}
}
Cu-diacetyl-bis(N4-methylthiosemicarbazone (Cu-ATSM) is an effective marker for the delineation of hypoxic tissue. Dosimetry calculations by the established Medical Internal Radionuclide Dose (MIRD) approach were performed with both animal and patient data. Human absorbed dose estimates extrapolated from rat data were based on the biodistribution of 61Cu… CONTINUE READING