Dosimetry and fluence measurements with a new irradiation arrangement for neutron capture therapy of tumours in mice.

@article{Pller1991DosimetryAF,
  title={Dosimetry and fluence measurements with a new irradiation arrangement for neutron capture therapy of tumours in mice.},
  author={F P{\"o}ller and Wolfgang Sauerwein and J{\"u}rgen Rassow},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={1991},
  volume={21 3},
  pages={179-82}
}
Incorporation of 10B in human tumours treated with fast neutrons would increase the local dose in the tumour. In tissue the neutrons are thermalized mainly causing the neutron capture reaction 10B (n,a) 7Li. The dose enhancement can be calculated using the thermal neutron fluence measured by activation of gold foils in a phantom. At a phantom depth of 5 cm a dose enhancement of (0.056 +/- 0.0028)% for each microgram of 10B per gram of tissue was determined in the tumour. A therapeutic gain by… CONTINUE READING

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