Dosimetric Predictors of Radiation-Induced Vaginal Stenosis After Pelvic Radiation Therapy for Rectal and Anal Cancer.

@article{Son2015DosimetricPO,
  title={Dosimetric Predictors of Radiation-Induced Vaginal Stenosis After Pelvic Radiation Therapy for Rectal and Anal Cancer.},
  author={Christina H. Son and Ethel B Law and Jung Hun Oh and Aditya P. Apte and T. J. Yang and Elyn R. Riedel and Abraham Jing-Ching Wu and Joseph O. Deasy and Karyn A. Goodman},
  journal={International journal of radiation oncology, biology, physics},
  year={2015},
  volume={92 3},
  pages={548-54}
}
PURPOSE Although vaginal stenosis (VS) is a recognized toxicity in women who receive pelvic radiation therapy (RT), the relationship between RT dose and the volume and extent of toxicity has not been analyzed. We modeled this relationship to identify predictors of VS. METHODS AND MATERIALS We evaluated 54 women, aged 29 to 78 years, who underwent pelvic RT for rectal or anal cancer during 2008 to 2011 and were enrolled in a prospective study evaluating vaginal dilator use. Maximum dilator… CONTINUE READING