Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy.

@article{Jin2009DosevolumeTA,
  title={Dose-volume thresholds and smoking status for the risk of treatment-related pneumonitis in inoperable non-small cell lung cancer treated with definitive radiotherapy.},
  author={Hekun Jin and Susan L. Tucker and Hui Helen Liu and Xiong Wei and Sue S Yom and Shu-lian Wang and Ritsuko Komaki and Yuhchyau Chen and Mary K. Martel and Radhe Mohan and James D. Cox and Zhongxing Liao},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2009},
  volume={91 3},
  pages={427-32}
}
PURPOSE To identify clinical risk factors and dose-volume thresholds for treatment-related pneumonitis (TRP) in patients with non-small cell lung cancer (NSCLC). METHODS AND MATERIALS Data were retrospectively collected from patients with inoperable NSCLC treated with radiotherapy with or without chemotherapy. TRP was graded according to Common Terminology Criteria for Adverse Events, version 3.0, with time to grade > or = 3 TRP calculated from start of radiotherapy. Clinical factors and dose… CONTINUE READING

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A little to a lot or a lot to a little? An analysis of pneumonitis risk from dose–volume histogram parameters of the lung in patients with lung cancer treated with 3-D conformal radiotherapy

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