Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients.

@article{Dhand1996DoseresponseTB,
  title={Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients.},
  author={Rajiv Dhand and Alex G. Duarte and Amal Jubran and John W. Jenne and James B. Fink and Patrick J. Fahey and Martin J. Tobin},
  journal={American journal of respiratory and critical care medicine},
  year={1996},
  volume={154 2 Pt 1},
  pages={
          388-93
        }
}
In nonintubated patients, metered-dose inhalers (MDIs) are accepted as the most convenient, efficient, and cost effective method of administering inhaled bronchodilators. Recent studies have demonstrated the efficacy of MDIs in ventilator-supported patients; however, the optimal dose of a bronchodilator from a MDI is unknown. We determined the response to increasing doses of albuterol administered by a MDI and cylindrical spacer to 12 mechanically ventilated patients with chronic obstructive… CONTINUE READING

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