Dose-response study of asthmatic volunteers exposed to nitrogen dioxide during intermittent exercise.

@article{Linn1986DoseresponseSO,
  title={Dose-response study of asthmatic volunteers exposed to nitrogen dioxide during intermittent exercise.},
  author={William S. Linn and Dr. Adil E. Shamoo and Edward L. Avol and J D Whynot and Karen R Anderson and Thierry Venet and Jack D. Hackney},
  journal={Archives of environmental health},
  year={1986},
  volume={41 5},
  pages={292-6}
}
Twenty-one mildly asthmatic volunteers were exposed to 0, 0.3, 1.0, and 3.0 ppm nitrogen dioxide (NO2) in purified background air in an environmental control chamber. Exposures were separated by 1-wk periods and occurred in random order. Each lasted 1 hr and included three 10-min bouts of moderately heavy exercise (mean ventilation rate 41 L/min). Exposure temperature was near 22 degrees C and relative humidity near 50%. Specific airway resistance and maximal forced expiratory performance were… CONTINUE READING

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