Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing.

@article{Bohadana1999DoseresponseSO,
  title={Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing.},
  author={Abraham B Bohadana and Ren{\'e} Peslin and Salim Megherbi and Dan B. Teculescu and Erik Andr{\'e} Sauleau and Pascal Wild and Q. T. Pham},
  journal={The European respiratory journal},
  year={1999},
  volume={13 2},
  pages={
          295-300
        }
}
  • Abraham B Bohadana, René Peslin, +4 authors Q. T. Pham
  • Published in
    The European respiratory…
    1999
  • Medicine
  • In population studies, the provocative dose (PD) of bronchoconstrictor causing a significant decrement in lung function cannot be calculated for most subjects. Dose-response curves for carbachol were examined to determine whether this relationship can be summarized by means of a continuous index likely to be calculable for all subjects, namely the two-point dose response slope (DRS) of mean resistance (Rm) and resistance at 10 Hz (R10) measured by the forced oscillation technique (FOT). Five… CONTINUE READING

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