Dose-response of ponies to parenteral Escherichia coli endotoxin.


The response of the pony to increasing doses of Escherichia coli endotoxin was evaluated using intravenous and intraperitoneal administration models. Marked changes were seen in all parameters measured following endotoxin administration. Leukopenia (neutropenia, lymphopenia) and thrombocytopenia were not dose-dependent. Similarly, elevated plasma fibrinogen… (More)


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@article{Burrows1981DoseresponseOP, title={Dose-response of ponies to parenteral Escherichia coli endotoxin.}, author={Geoffrey E. Burrows}, journal={Canadian journal of comparative medicine : Revue canadienne de medecine comparee}, year={1981}, volume={45 2}, pages={207-10} }