Dose-response models and methods of risk prediction and causation estimation.

  title={Dose-response models and methods of risk prediction and causation estimation.},
  author={Frederick H. Edwards},
  journal={Seminars in nuclear medicine},
  volume={16 2},
Dose-response models are mathematical expressions that describe the relationship between absorbed dose and radiogenic effects. The limited quality and quantity of human dose-response data make it necessary to use fairly simplistic models. Most current low-LET data support the linear-quadratic model in which radiogenic effects are linearly dependent at low doses and then become quadratically curved at higher doses. Some types of effects never exhibit a quadratic component, remaining linear over… CONTINUE READING

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