Dose-related neurocognitive effects of marijuana use
@article{Bolla2002DoserelatedNE, title={Dose-related neurocognitive effects of marijuana use}, author={Karen I. Bolla and K. Brown and Dana A. Eldreth and Kimberly Tate and J. L. Cadet}, journal={Neurology}, year={2002}, volume={59}, pages={1337 - 1343} }
BACKGROUND
Although about 7 million people in the US population use marijuana at least weekly, there is a paucity of scientific data on persistent neurocognitive effects of marijuana use. [] Key MethodMETHODS
A battery of neurocognitive tests was given to 28-day abstinent heavy marijuana abusers.
RESULTS
As joints smoked per week increased, performance decreased on tests measuring memory, executive functioning, psychomotor speed, and manual dexterity.
579 Citations
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The results indicate an absence of marked long-term residual effects of marijuana use on cognitive abilities.
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Adolescents demonstrate persisting deficits related to heavy marijuana use for at least six weeks following discontinuation, particularly in the domains of learning, memory, and working memory, which suggest adolescents appear more adversely affected by heavy use than adults.
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The general pattern of results suggested that, even after a month of monitored abstinence, adolescent marijuana users demonstrate subtle neuropsychological deficits compared with nonusers, suggesting that frequent marijuana use during adolescence may negatively influence neuromaturation and cognitive development.
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The current study findings extend the literature by demonstrating the complex relationship between HIV status and MJ use on neurocognitive and clinical outcomes.
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