Corpus ID: 79426736

Dose proportionality comparison of beta1 blocking activity of cetamolol hydrochloride and atenolol in normal subjects

  title={Dose proportionality comparison of beta1 blocking activity of cetamolol hydrochloride and atenolol in normal subjects},
  author={M. Klausner and J. Coelho and D. Dvornik and C. Perdomo and D. Shand and D. Weidler and J. Mullane},
  journal={Current Therapeutic Research-clinical and Experimental},
9 Citations
Monitoring the adverse profile of atenolol--a collaborative study.
Better patient selection, optimal dose, and racial factor and season might be operating to bring down ADR to atenolol in Indian patients could have reduced the frequency of ADR in the present study. Expand
Atenolol. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders.
After many years of clinical usage atenolol is a well established treatment option in several areas of cardiovascular medicine such as mild to moderate hypertension and stable angina pectoris and has shown potential in the treatment of some cardiac arrhythmias and has been associated with reduced cardiovascular mortality in patients with hypertension and with myocardial infarction. Expand
Antihypertensive Efficacy of Cetamolol: A Dose‐Titrated Study
Treatment with cetamolol in titrated oral doses of 5‐10‐15 mg or 15‐25‐50 mg once daily was safe and effective in patients with mild to moderate hypertension. Expand
Cardioselectivity of Cetamolol Compared With Atenolol and Nadolol
Data from the three studies demonstrate that cetamolol is cardioselective relative to nadolol and that, in contrast to atenolol, cardiosity appears to increase at the higher dose, and that the antagonism of beta‐2‐mediated responses to titrated doses of intravenous isoproterenol by low and high doses of each drug is evaluated. Expand
Effect of Cetamolol on Epinephrine‐Induced Hypokalemia
The results of this study indicate that cetamolol blocks epinephrine‐induced hypokalemia and associated electrocardiographic changes. Expand
Pharmacokinetics of Cetamolol in Hypertensive Patients with Normal and Compromised Renal Function
Dosing recommendations are suggested for patients who have compromised renal function because of the effects of renal function on the pharmacokinetic parameters of cetamolol, as the severity of renal impairment increased. Expand
Effects of chronic cetamolol therapy on resting, ambulatory, and exercise blood pressure and heart rate
It is suggested that cetamolol reduces BP without lowering HR at rest, during periods of increased adrenergic activity such as work and dynamic exercise, both HR and BP are reduced. Expand