Dose prescription and treatment planning based on FMISO-PET hypoxia.

  title={Dose prescription and treatment planning based on FMISO-PET hypoxia.},
  author={Iuliana Toma-Dasu and Johan Uhrdin and Laura Antonovic and Alexandru Dasu and Sandra Nuyts and Piet Dirix and Karin Haustermans and Anders Brahme},
  journal={Acta oncologica},
  volume={51 2},
PURPOSE The study presents the implementation of a novel method for incorporating hypoxia information from PET-CT imaging into treatment planning and estimates the efficiency of various optimization approaches. Its focuses on the feasibility of optimizing treatment plans based on the non-linear conversion of PET hypoxia images into radiosensitivity maps from the uptake properties of the tracers used. MATERIAL AND METHODS PET hypoxia images of seven head-and-neck cancer patients were used to… CONTINUE READING


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