Dose-finding study of oral desogestrel with testosterone pellets for suppression of the pituitary-testicular axis in normal men.

@article{Martin2000DosefindingSO,
  title={Dose-finding study of oral desogestrel with testosterone pellets for suppression of the pituitary-testicular axis in normal men.},
  author={Cameron W Martin and Simon C. Riley and Dawn Everington and Nigel Patrick Groome and Rudolph A. Riemersma and David T Baird and Richard A. Anderson},
  journal={Human reproduction},
  year={2000},
  volume={15 7},
  pages={1515-24}
}
Prototype hormonal male contraceptive regimens generally achieve only incomplete suppression to azoospermia with potentially adverse metabolic effects. We have carried out a short-term dose-finding study to investigate the potential of an oral gestogen, desogestrel, with testosterone pellets. Normal men received a single dose of 300 mg testosterone with 75… CONTINUE READING