Dose escalated neoadjuvant chemoradiotherapy with dose-painting intensity-modulated radiation therapy and improved pathologic complete response in locally advanced esophageal cancer.

@article{Venkat2017DoseEN,
  title={Dose escalated neoadjuvant chemoradiotherapy with dose-painting intensity-modulated radiation therapy and improved pathologic complete response in locally advanced esophageal cancer.},
  author={Puja S. Venkat and Ravi Shridhar and Arash Olyie Naghavi and Sarah E. Hoffe and Khaldoun Almhanna and Jose Mario Pimiento and J-P Fontaine and Yazan A. Abuodeh and Ken Meredith and Jessica M. Frakes},
  journal={Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus},
  year={2017},
  volume={30 7},
  pages={
          1-9
        }
}
We compared pathologic complete response (pCR) rate, toxicity, and postoperative complications between patients treated preoperatively with 50.4 Gy versus dose escalation with dose-painting intensity-modulated radiation therapy (dp-IMRT) to 56 Gy in locally advanced esophageal cancer. We evaluated esophageal cancer patients treated between 2006 and 2014… CONTINUE READING