Dose escalated, hypofractionated radiotherapy using helical tomotherapy for inoperable non-small cell lung cancer: preliminary results of a risk-stratified phase I dose escalation study.

@article{Adkison2008DoseEH,
  title={Dose escalated, hypofractionated radiotherapy using helical tomotherapy for inoperable non-small cell lung cancer: preliminary results of a risk-stratified phase I dose escalation study.},
  author={Jarrod B. Adkison and Deepak Khuntia and Soren M. Bentzen and George M Cannon and Wolfgang A. Tom{\'e} and Hazim A Jaradat and William J Walker and Anne M. Traynor and Tracey Lee Weigel and Minesh P. Mehta},
  journal={Technology in cancer research & treatment},
  year={2008},
  volume={7 6},
  pages={441-7}
}
To improve local control for inoperable non-small cell lung cancer (NSCLC), a phase I dose escalation study for locally advanced and medically inoperable patients was devised to escalate tumor dose while limiting the dose to organs at risk including the esophagus, spinal cord, and residual lung. Helical tomotherapy provided image-guided IMRT, delivered in a… CONTINUE READING