Dose-effect of inorganic tin on biochemical indices in rats.

  title={Dose-effect of inorganic tin on biochemical indices in rats.},
  author={Masayoshi Yamaguchi and Ryota Saito and Shigeru Okada},
  volume={16 3},
The dose-effect of stannous chloride on biochemical indices was examined in weanling male rats given oral doses of 0.3, 1.0 and 2.0 mg/kg at 12-h intervals for 90 days. The 3.0 mg/kg dose caused significant decreases of the relative weights of the femur, calcium concentration, lactic dehydrogenase and alkaline phosphatase activities in the serum, succinate dehydrogenase activity in the liver, and calcium content and acid phosphatase activity in the femoral diaphysis and epiphysis. Of the above… CONTINUE READING