Dose-dependent variation in the disposition of eugenol in the rat

@article{Sutton1985DosedependentVI,
  title={Dose-dependent variation in the disposition of eugenol in the rat},
  author={James D. Sutton and S. A. Sangster and John Caldwell},
  journal={Biochemical Pharmacology},
  year={1985},
  volume={34},
  pages={465-466}
}
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23 Citations
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23 Citations

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Citation Type

High doses of eugenol cause structural and functional damage to the rat liver.
Update to RIFM fragrance ingredient safety assessment, eugenol, CAS Registry Number 97-53-0.
  • A. Api, D. Belsito, Y. Tokura
  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2022
RIFM fragrance ingredient safety assessment, 2-methoxy-4-propylphenol, CAS Registry Number 2785-87-7.
  • A. Api, D. Belsito, S. Tsang
  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2020
Modulation of feed composition is able to make hens less attractive to the poultry red mite Dermanyssus gallinae
TLDR
Behavioural choice tests to compare the effect of the modified and unmodified-host odours on thePRM show that some of the plant-originating emitted VOCs and the modified whole-hen odours were repellent to the PRM.
RIFM fragrance ingredient safety assessment, Eugenol, CAS Registry Number 97-53-0.
  • A. Api, D. Belsito, D. K. Wilcox
  • Biology, Environmental Science
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2016
In vivo and in vitro metabolism of aspirin eugenol ester in dog by liquid chromatography tandem mass spectrometry.
TLDR
Investigation into the metabolic process in target animal species of aspirin eugenol ester will help to illustrate its mechanism of action and to establish its residual mark compound to formulate its dosage.
Compounds for controlled release of active molecules
The present invention relates to the perfume field. More particularly, the present invention relates to compounds having at least one β-glucuronide group capable of liberating perfumed alcohol. The…
14 – Constituent profiles
Coffee aroma constituents and odorant metabolites in human urine
TLDR
Investigation of urine samples obtained after consumption of common dosages of coffee revealed that some odorants were present at considerably elevated concentrations after the ingestion of coffee, confirmed by the odor profiles of the respective urine samples during sensory analysis.
Effect of essential oils on gut bacteria and functionality in the pig
TLDR
This document summarizes current capabilities, research and operational priorities, and plans for further studies that were established at the 2015 USGS workshop on quantitative hazard assessments of earthquake-triggered landsliding and liquefaction in the western hemisphere.
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References

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Dose dependent conversion of estragole in the rat and mouse to the carcinogenic metabolite, 1'-hydroxyestragole.
Absorption, metabolism and excretion of safrole in the rat and man.
Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
TLDR
Twenty-three naturally occurring and synthetic alkenylbenzene derivatives structurally related to the hepatocarcinogen safrole were assayed for their hepatocARCinogenicity in mice to identify benign skin tumors that could be promoted with croton oil.