Dose-dependent responses of pigs infected with foot-and-mouth disease virus O/JPN/2010 by the intranasal and intraoral routes

Abstract

Foot-and-mouth disease virus (FMDV) infection was successfully initiated in pigs by intraoral inoculation of both 106 and 103 TCID50 of FMDV O/JPN/2010 isolated from the 2010 epidemic in Japan. By intranasal inoculation, infection was established in pigs with 106 TCID50 of the isolate, but not with 103 TCID50 of the isolate. In the pigs inoculated with 106… (More)
DOI: 10.1007/s00705-014-2239-4

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