Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men.

  title={Dose-dependent responses of myofibrillar protein synthesis with beef ingestion are enhanced with resistance exercise in middle-aged men.},
  author={Meghann J Robinson and Nicholas A. Burd and Leigh Breen and Tracy Rerecich and Yifan Yang and Amy J. Hector and Steven K. Baker and Stuart M Phillips},
  journal={Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme},
  volume={38 2},
Aging impairs the sensitivity of skeletal muscle to anabolic stimuli, such as amino acids and resistance exercise. Beef is a nutrient-rich source of dietary protein capable of stimulating muscle protein synthesis (MPS) rates in older men at rest. To date, the dose-response of myofibrillar protein synthesis to graded ingestion of protein-rich foods, such as beef, has not been determined. We aimed to determine the dose-response of MPS with and without resistance exercise to graded doses of beef… 

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