Dose-dependent half-life of glycine

@article{Hahn1993DosedependentHO,
  title={Dose-dependent half-life of glycine},
  author={R. Hahn},
  journal={Urological Research},
  year={1993},
  volume={21},
  pages={289-291}
}
  • R. Hahn
  • Published 1993
  • Medicine
  • Urological Research
    • SummaryThe serum concentration of glycine was measured at hourly intervals after administration of between 10 and 91 g glycine to 17 patients undergoing transurethral resection of the prostate and of between 15 and 22 g glycine to 18 volunteers by intravenous infusion. [...] Key Result The apparent half-life of glycine varied 10-fold (range 26–245 min) and increased in direct proportion to the amount of glycine given. This result can be explained by assuming a marked intracellular accumulation of a surplus of…Expand Abstract
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 15 REFERENCES
    Amino acid concentrations in serum and urine after intravenous infusion of 1.5% glycine in prostatectomy patients.
    13
    Serum amino acid patterns and toxicity symptoms following the absorption of irrigant containing glycine in transurethral prostatic surgery
    21
    Intravenous infusion of irrigating fluids containing glycine or mannitol with and without ethanol.
    38
    Glycine solution as an irrigating agent during transurethral prostatic resection. Glycine concentrations in blood plasma.
    6
    Effects of isosmotic and hyperosmotic glycine solutions on the fluid balance in conscious sheep.
    9
    Haemodynamics and fluid balance after intravenous infusion of 1.5% glycine in sheep
    19
    Amino acid concentrations in plasma and skeletal muscle after transurethral resection syndrome.
    10
    Irrigating fluid absorption and blood loss during transurethral resection of the prostate studied with a regular interval monitoring (RIM) method.
    24
    Visual disturbances, serum glycine levels and transurethral resection of the prostate.
    18
    Transurethral resection of the prostate, serum glycine levels, and ocular evoked potentials.
    34