Dose dependent effects of inhaled ethylene oxide on spermatogenesis in rats.

@article{Mori1991DoseDE,
  title={Dose dependent effects of inhaled ethylene oxide on spermatogenesis in rats.},
  author={Koichi Mori and Masanobu Kaido and Kennichiro Fujishiro and Naohide Inoue and Osamu Koide and Hajime Hori and Isamu Tanaka},
  journal={British journal of industrial medicine},
  year={1991},
  volume={48 4},
  pages={
          270-4
        }
}
Male Wistar rats were exposed to ethylene oxide (EO) at concentrations of 50, 100, or 250 ppm for six hours a day, on five days a week for 13 weeks. Dose effect relations of inhaled EO on spermatogenesis were evaluated from testicular and epididymal weights, histopathological changes and lactate dehydrogenase X (LDH X) activity in the testis, and sperm counts and sperm head abnormalities in the epididymis. At 250 ppm, a decrease in epididymal weights, slight degenerations in the seminiferous… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 21 references

Evaluation of reproductive toxicity by testicular sperm head counts

ML Meistrich
Journal of the American College of Toxicology • 1989

Increased sperm abnormalities due to dietary restriction

H Komatsu, T Kakizoe, T Niijima, T Kawachi, T Sugimura
Mutat Res • 1982

Quantitative correlation between testicular stem cell survival , sperm production , and fertility in the mouse after treatment with different cytotoxic agents

ML Meistrich
J Androl • 1982