Dose-dependent effects of atorvastatin on myocardial infarction

  title={Dose-dependent effects of atorvastatin on myocardial infarction},
  author={O L Barbarash and Olga V Gruzdeva and Evgenya Uchasova and Ekaterina Belik and Yulia Dyleva and Victoria N. Karetnikova},
  booktitle={Drug design, development and therapy},
BACKGROUND Dyslipidemia is a key factor determining the development of both myocardial infarction (MI) and its subsequent complications. Dyslipidemia is associated with endothelial dysfunction, activation of inflammation, thrombogenesis, and formation of insulin resistance. Statin therapy is thought to be effective for primary and secondary prevention of complications associated with atherosclerosis. METHODS This study examined 210 patients with Segment elevated MI (ST elevated MI) who were… CONTINUE READING


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