Corpus ID: 32775583

Dose-dependent cholesterolemic activity of tocotrienols.

@article{Khor2002DosedependentCA,
  title={Dose-dependent cholesterolemic activity of tocotrienols.},
  author={Hunteik Khor and T. Ng and Raajeswari Rajendran},
  journal={Malaysian journal of nutrition},
  year={2002},
  volume={8 2},
  pages={
          157-66
        }
}
Tocotrienols and tocopherols are isoforms of vitamin E. Vitamin E may exhibit antioxidant, prooxidant and non-antioxidant activities depending upon circumstances. In this study, the effect of tocotrienols and a-tocopherol on the activities of HMG CoA reductase and cholesterol 7 a-hydroxylase was investigated. Pure tocotrienols were isolated from palm fatty acid distillate and pure a-tocopherol was obtained commercially. Guinea pigs were treated with different dosages of tocotrienols and a… Expand
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