Dose dependent alterations in epididymal sperm counts of cisplatin or carboplatin treated male wistar rats

Abstract

Infertility is a major concern for young men of reproductive age under-going chemotherapy. Unfortunately chemotherapeutic treatment for neoplastic diseases commonly impairs fertility either temporally or permanently. In general, chemotherapeutic agents target rapidly dividing germ cells, and it is therefore results in impairment of spermatogenesis leading… (More)

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