Dose-dependent absorption of chlorogenic acids in the small intestine assessed by coffee consumption in ileostomists.

@article{Erk2012DosedependentAO,
  title={Dose-dependent absorption of chlorogenic acids in the small intestine assessed by coffee consumption in ileostomists.},
  author={Thomas Erk and Gary Williamson and Mathieu Renouf and Cynthia Marmet and Heike Steiling and Fabiola Dionisi and Denis Barron and Ralf Melcher and Elke Richling},
  journal={Molecular nutrition & food research},
  year={2012},
  volume={56 10},
  pages={1488-500}
}
SCOPE Until now, the question of how the ingested doses of chlorogenic acids (CGA) from coffee influence their absorption and metabolism remains unresolved. To assess absorption in the small intestine, we performed a dose-response study with a randomized, double-blinded, crossover design with ileostomist subjects. METHODS AND RESULTS After a polyphenol-free diet, the volunteers consumed, on three separate occasions, coffee with different total CGA contents (high 4525 μmol; medium 2219 μmol… CONTINUE READING
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