Dose dependence of the 5-HT agonist quipazine in facilitating spinal stepping in the rat with epidural stimulation

@article{Ichiyama2008DoseDO,
  title={Dose dependence of the 5-HT agonist quipazine in facilitating spinal stepping in the rat with epidural stimulation},
  author={Ronaldo M Ichiyama and Yury P. Gerasimenko and Devin L. Jindrich and Hui Zhong and V. Reggie Edgerton},
  journal={Neuroscience Letters},
  year={2008},
  volume={438},
  pages={281-285}
}
Epidural electrical stimulation (ES) at spinal cord segment L2 can produce coordinated step-like movements in completely spinalized adult rats [R.M. Ichiyama, Y.P. Gerasimenko, H. Zhong, R.R. Roy, V.R. Edgerton, Hindlimb stepping movements in complete spinal rats induced by epidural spinal cord stimulation, Neurosci. Lett. 383 (2005) 339-344]. Plantar placement of the paws, however, was rarely observed. Here, we sought to determine the dose dependence of a 5-HT agonist (quipazine) on stepping… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

Variability in step training enhances locomotor recovery after a spinal cord injury.

  • The European journal of neuroscience
  • 2012
VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND

Step training reinforces specific spinal locomotor circuitry in adult spinal rats.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2008
VIEW 2 EXCERPTS
CITES METHODS