Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses

Abstract

The oral proteasome inhibitor ixazomib has been approved by regulatory authorities around the world, including in the United States and the European Union, for the treatment of patients with multiple myeloma (MM) who have received at least one prior therapy, based on the pivotal phase III TOURMALINE-MM1 study. The objective of this study was to… (More)
DOI: 10.1007/s11523-017-0524-3

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Cite this paper

@inproceedings{Gupta2017DoseAS, title={Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses}, author={Neeraj K. Gupta and Huyuan Yang and Michael J. Hanley and Steven Y Zhang and Rachael Liu and Shaji K Kumar and Paul G Richardson and Tom{\'a}s Sk{\'a}cel and Karthik Venkatakrishnan}, booktitle={Targeted Oncology}, year={2017} }