Dose-Related Modulation of Event-Related Potentials to Novel and Target Stimuli by Intravenous Δ9-THC in Humans

@article{Dsouza2012DoseRelatedMO,
  title={Dose-Related Modulation of Event-Related Potentials to Novel and Target Stimuli by Intravenous Δ9-THC in Humans},
  author={Deepak Cyril D'souza and Daniel J Fridberg and Patrick D. Skosnik and Ashley H Williams and Brian J. Roach and Nagendra Singh and Michelle Carbuto and Jacqueline Elander and Ashley Schnakenberg and Brian Pittman and Richard Sewell and Mohini Ranganathan and Daniel H. Mathalon},
  journal={Neuropsychopharmacology},
  year={2012},
  volume={37},
  pages={1632-1646}
}
Cannabinoids induce a host of perceptual alterations and cognitive deficits in humans. However, the neural correlates of these deficits have remained elusive. The current study examined the acute, dose-related effects of delta-9-tetrahydrocannabinol (Δ9-THC) on psychophysiological indices of information processing in humans. Healthy subjects (n=26) completed three test days during which they received intravenous Δ9-THC (placebo, 0.015 and 0.03 mg/kg) in a within-subject, double-blind… CONTINUE READING

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