Dose-Dependent Immunomodulation of Human Dendritic Cells by the Probiotic Lactobacillus rhamnosus Lcr35

@inproceedings{Evrard2011DoseDependentIO,
  title={Dose-Dependent Immunomodulation of Human Dendritic Cells by the Probiotic Lactobacillus rhamnosus Lcr35},
  author={Bertrand Evrard and Sophie Coudeyras and Annie Dosgilbert and Nicolas Charbonnel and Josette Alam{\'e} and Arlette Tridon and Christiane Forestier},
  booktitle={PloS one},
  year={2011}
}
The response of the immune system to probiotics remains controversial. Some strains modulate the cytokine production of dendritic cells (DCs) in vitro and induce a regulatory response, while others induce conversely a pro-inflammatory response. These strain-dependent effects are thought to be linked to specific interactions between bacteria and pattern recognition receptors. We investigated the effects of a well characterized probiotic strain, Lactobacillus rhamnosus Lcr35, on human monocyte… CONTINUE READING
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Microbes and Health Sackler Colloquium: Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways

  • P van Baarlen, F Troost, C van der Meer, G Hooiveld, M Boekschoten
  • Proc Natl Acad Sci U S A [Epub ahead of print]
  • 2010
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