Dose‐Related Effects of Estazolam on Sleep of Patients with Insomnia

@article{Roehrs1983DoseRelatedEO,
  title={Dose‐Related Effects of Estazolam on Sleep of Patients with Insomnia},
  author={Timothy Roehrs and Frank J. Zorick and Norman John Lord and Gail Koshorek and Thomas Roth},
  journal={Journal of Clinical Psychopharmacology},
  year={1983},
  volume={3},
  pages={152–156}
}
The dose range of estazolam for hypnotic effects was studied in seven men and eight women (mean age 30.3 ± 8.6 years) who complained of insomnia and had polysomnographic evidence of disturbed sleep. Patients slept in the laboratory and were monitored using standard polysomnographic techniques. Four consecutive nights in the laboratory with placebo, which served as baseline and screening nights, were followed by five 2-night drug administration periods separated by 5-day drug washout periods… 
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