Dosage requirements for runt in the segmentation of Drosophila embryos.

@article{Gergen1986DosageRF,
  title={Dosage requirements for runt in the segmentation of Drosophila embryos.},
  author={J Peter Gergen and Eric F. Wieschaus},
  journal={Cell},
  year={1986},
  volume={45 2},
  pages={289-99}
}
The runt gene is required in a Drosophila embryo for normal segmentation. We investigate this requirement by analyzing runt mutations of varying strength and by manipulating wild-type gene dosage. Elimination of runt causes periodic deletions in the segmentation pattern which are spaced at two segment intervals along the antero-posterior axis. The pattern… CONTINUE READING