Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity.

@article{Weiss1998DorsoventralPI,
  title={Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity.},
  author={Joseph B. Weiss and Tonia Von Ohlen and Dervla M. Mellerick and Gregory R Dressler and Chris Q Doe and Matthew P Scott},
  journal={Genes & development},
  year={1998},
  volume={12 22},
  pages={3591-602}
}
One of the first steps in neurogenesis is the diversification of cells along the dorsoventral axis. In Drosophila the central nervous system develops from three longitudinal columns of cells: ventral cells that express the vnd/nk2 homeobox gene, intermediate cells, and dorsal cells that express the msh homeobox gene. Here we describe a new Drosophila homeobox gene, intermediate neuroblasts defective (ind), which is expressed specifically in the intermediate column cells. ind is essential for… CONTINUE READING
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