Dorsally and ventrally derived oligodendrocytes have similar electrical properties but myelinate preferred tracts.

@article{Tripathi2011DorsallyAV,
  title={Dorsally and ventrally derived oligodendrocytes have similar electrical properties but myelinate preferred tracts.},
  author={Richa B. Tripathi and Laura E. Clarke and Valeria Burzomato and Nicoletta Kessaris and Patrick Anderson and David Attwell and William D Richardson},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 18},
  pages={6809-6819}
}
In the developing spinal cord, most oligodendrocyte precursors (OLPs) arise from the ventral ventricular zone (VZ) under the influence of Sonic Hedgehog, but a minority are generated from the dorsal VZ in a Hedgehog-independent manner. In the developing forebrain too, OLPs arise from both the ventral and the dorsal VZ. It is not known whether dorsally and ventrally derived oligodendrocyte (OL) lineage cells have different properties. We generated a dual reporter mouse line to color code… CONTINUE READING