Dorsal-ventral midline signaling in the developing Drosophila eye.

  title={Dorsal-ventral midline signaling in the developing Drosophila eye.},
  author={Atsushi Sato and Andrew Stephen Tomlinson},
  volume={134 4},
Boundaries between different cell types play key roles in many developmental patterning processes. They can be established by various mechanisms, and signaling between the different cell types can occur in a number of ways. One mechanism of crossboundary signaling is controlled by the Notch (N)-modifying protein Fringe (Fng). At the Drosophila wing dorsal-ventral (D-V) border, the mechanism by which an Fng(+)-Fng(-) interface controls local N activation has been well characterized. A similar N… CONTINUE READING

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